About Altogen Biosystems

Altogen Biosystems is a biotechnology company focused on development of kits and reagents for intracellular delivery of biomolecules and pharmaceuticals. Our product line of over 70 pre-optimized transfection kits and transfection protocols allows efficient transfection of siRNA, plasmid DNA, mRNA, and microRNA into broad range of cancer cell lines and primary cell types.

ALTOGEN® In Vivo Transfection Reagents are manufactured using compounds of different sizes, chemichal and physical properties, such as nanoparticles, liposomes, and biodegradable polymers, allowing targeted delively of siRNA and DNA into particular tissues and organs in vivo.

Altogen Custom Services offer RNAi services (transient and stable gene silencing), generation of stable cell lines, siRNA transfection and library screening, assay development, and other biology research services.

Transfection Products

Transfection is a process of artificial introduction of nucleic acids into cells in vitro or in vivo. One of the most common transfection approaches is using electrostatic lipids in a form of liposome, micelle, etc. These structures merge with a plasma membrane, delivering cargo molecules inside the cell. Lipids are suitable for introduction of biologically active substances, such as peptides, proteins, DNA,  RNA, siRNA, and microRNA in certain types of eukaryotic cells. Unfortunately, there is no single reagent, kit, or transfection method that can be applied to all types of cells; transfection efficiencies vary dramatically depending on transfection method, reagent, protocol, and cell type being used.

Altogen Biosystems presents featured cell line-specific transfection kits: Fibroblast, HepG2, A549, MDA-MB, HEK-293, Astrocytes, CHO, COS-7, HUVEC, LNCaP. Each kit contains cell type specific Transfection Reagent, Transfection Enhancer Reagent, and recommended transfection protocol.

Nanoparticle-based, Lipid-based, and Polymer-based ALTOGEN® In Vivo Transfection Reagents enable delivery of functional RNA and DNA molecules in vivo.

Cell Transfection Resource

Visit Altogen's Cell Transfection Resource: RNAi applications, stable and transient transfection, electroporation, microinjection, non-viral and virus-mediated gene delivery, liposome- and nanoparticle-based transfection reagents for in vitro and in vivo applications.